Coagulase Negative Staphylococci Isolated from Blood Cultures at Anosiala University Hospital Center, Antananarivo

Lalaina Mamenosoa RAKOTONDRAOELINA; Arinomenjanahary Malalanandrianina RAKOTOARISOA; Jean de La Croix JAONASOA; Andry Maharo ANDRIANARIVELO; Andry RASAMINDRAKOTROKA

Lalaina Mamenosoa RAKOTONDRAOELINA
Arinomenjanahary Malalanandrianina RAKOTOARISOA
Jean de La Croix JAONASOA
Andry Maharo ANDRIANARIVELO
Andry RASAMINDRAKOTROKA

Keywords: Blood culture, Coagulase negative Staphylococci, Prevalence, Resistance

Abstract

Blood cultures are bacteriological examinations to be carried out to confirm bacteremia caused by pathogenic germs. Coagulase-negative Staphylococci are so-called opportunistic bacteria that can become pathogenic for their host, especially in immunocompromised individuals. The main objective of this study was to determine the prevalence of coagulase-negative Staphylococci isolated from blood cultures and their antibiotic resistance at the Anosiala University Hospital Center. This is a retrospective descriptive study of blood culture examinations carried out in the bacteriology laboratory of the Anosiala University Hospital Center. It was carried out from January 2020 to December 2022 for a period of 2 years. Among 274 blood samples received during this period, 38 isolated cases of coagulase-negative Staphylococci were recorded, representing a prevalence of 13.86%. All blood cultures positive for coagulase-negative Staphylococci were isolated from hospitalized patients: pediatric department in 85% of cases (32/38), followed by intensive care in 10% of cases (4/38), then medicine unit in 5% of cases (2/38). In this study, 60% were identified resistant to methicillin. The most active molecules were Pristinamycin and Vancomycin. Carrying out blood culture in a developing country like Madagascar requires consensus both in the collection and in the interpretation of positive results. Clinico-biological consultation remains essential to distinguish real bacteremia from contamination.

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