A Brief Insight into a Common Short Term Sequel of Covid-19 Vaccination against the SARS-Cov-2 Virus: A Case History and Report of Shoulder Pain Syndrome

  • A. S. Edunjobi
  • H. E. Norton
  • B. O. Aina
  • A. N. Oluwasanya
  • A. M. Babs-Edunjobi
Keywords: covid-19 pandemic/vaccine, SARS-Cov-2 virus, shoulder pain syndrome

Abstract

Background: The approval of the covid-19 vaccines against the SARS-Cov-2 (Severe Acute Respiratory Syndrome Coronavirus-2) strain has proven very effective, reducing hospitalization and overall mortality and morbidity. Shoulder pain is a common symptom after any intramuscular vaccination, including against the novel covid-19 infection. However, this is not as intensely reported sequel as the involvement of other body systems. This discussion reports shoulder pain syndrome as a short-term sequel post-covid-19 vaccination in what could be described as a SIRVA (shoulder injury related to vaccine administration) - like presentation.

Objective: The objective of this study is to give a brief insight into a common short term sequel of covid-19 vaccination against the SARS-CoV-2 virus, with shoulder pain syndrome as case study.

Method: This is a retrospective cohort study of collated reports from medical colleagues and researchers resident in Canada, the United Kingdom, Nigeria and within the United States; in public and private practices involving patients whether previously infected with the SARS-Cov-2 virus or not, but that have had any of the covid-19 vaccine approved for use in their respective country injected between March 1st and December 31st 2022. Data were obtained from the various medical records applicable in each practitioner’s domain and through direct interviews. A total of eighty two (82) patients were reviewed. Descriptive analysis and a case history of the study were reported.

Results: Eighty two (82) people were retrospectively reviewed across age, sex, exposure to the covid-19 vaccines and geographical distribution over the nine month period. There is a female preponderance of forty three or 52.4%; against thirty nine males which accounts for 47.6% of total cases reviewed. The age range is between ≥18 and ≤99 year-old. One of these patients is herein reported as case study.

Conclusion: The findings in this study have further confirmed a significant relationship between covid-19 vaccination and the development of shoulder pain in a SIRVA-like presentation. It is therefore hoped that this will encourage relevant stakeholders to provide ready-made interventions for this presentation, thereby preventing avoidable disability, the apprehension of post-vaccination adverse events and vaccine hesitancy in the general population.

References

Atanasoff, S., Ryan, T., Lightfoot, R., & Johann-Liang, R. (2010). Shoulder injury related to vaccine administration (SIRVA). Vaccine, 28, 8049-52. https://doi.org/10.1016/j.vaccine.2010.10.005.
Bancsi, A., Houle, S.K.D., & Grindrod, K.A. (2018). Getting it in the right spot: Shoulder injury related to vaccine administration (SIRVA) and other injection site events. Can Pharm J (Ott), 151, 295-9. https://doi.org/10.1177/1715163518790771.
Barnes, M.G., Ledford, C., & Hogan, K. (2012). A “needling” problem: shoulder injury related to vaccine administration. J Am Board Fam Med, 25, 919–922. https://doi.org/10.3122/jabfm.2012.06.110334.
Bodor, M. & Montalvo, E. (2007). Vaccination-related shoulder dysfunction. Vaccine, 25(4), 585–587.
Cagle, P.J., Jr. (2021). Shoulder Injury after Vaccination: a Systematic Review. Rev Bras Ortop (Sao Paulo), 56(3), 299–306. https://doi.org/10.1055/s-0040-1719086.
Centers for Disease Control and Prevention. (2015). Epidemiology and prevention of vaccine-preventable diseases. [Accessed June 3, 2019]. https://www.cdc.gov/vaccines/pubs/pinkbook/vac-admin.html.
Chang, A.Y., Cullen, M.R., Harrington, R.A., & Barry, M. (2021). The impact of novel coronavirus COVID-19 on noncommunicable disease patients and health systems: A review. J. Intern. Med, 289, 450–462.
Cook, I.F. (2014). Subdeltoid/subacromial bursitis associated with influenza vaccination. Hum Vaccin Immunother, 10, 605-6. https://doi.org/10.4161/hv.27232.
Hibbs, B.F., Ng, C.S., Museru, O., et al. (2020). Reports of atypical shoulder pain and dysfunction following inactivated influenza vaccine, Vaccine Adverse Event Reporting System (VAERS), 2010–2017. Vaccine, 38(5), 1137–1143.
Honarmand, A.R., Mackey, J., & Hayeri, R. (2021) Shoulder injury related to vaccine administration (SIRVA) following mRNA COVID-19 vaccination: report of 2 cases of subacromial-subdeltoid bursitis. Radiol Case Rep, 16(12), 3631–4. https://doi.org/10.1016/j.radcr.2021.08.019
Institute of Medicine. Adverse effects of vaccines: evidence and causality. (2011). [Accessed June 3, 2019]. http://www.nationalacademies.org/hmd/~/media/Files/Report%20Files/2011/Adverse-Effects-of-Vaccines-Evidence-and-Causality/Vaccine-report-brief-FINAL.pdf.
Jęśkowiak, I., Wiatrak, B., Grosman-Dziewiszek, P., & Szeląg, A. (2021). The incidence and severity of post-vaccination reactions after vaccination against covid-19. Vaccines (Basel), 9(5), 502. https://doi.org/10.3390/vaccines9050502.
Kuether, G., Dietrich, B., Smith, T., Peter, C., & Gruessner, S. (2011). Atraumatic osteonecrosis of the humeral head after influenza A-(H1N1) v-2009 vaccination. Vaccine, 29(40), 6830–6833.
MacDonald, N.E., Eskola, J., Liang, X., Chaudhuri, M., Dube, E., Gellin, B., Goldstein, S., Larson, H., Manzo, M.L., Reingold, A., et al. (2015). Vaccine hesitancy: Definition, scope and determinants. Vaccine, 33, 4161–4164.
Martín Arias, L.H., Sanz Fadrique, R., Sáinz Gil, M., & Salgueiro-Vazquez, M.E. (2017). Risk of bursitis and other injuries and dysfunctions of the shoulder following vaccinations. Vaccine, 35, 4870–4876. https://doi.org/10.1016/j.vaccine.2017.07.055.
Majumder, M. A. A., Singh, K., Johnson, W. M. S., Rajasundaram, A., Gupta, S., Gaur, U., ... & Razzaque, M. S. (2023). Evaluation of short-term side effects following the first dose of COVID-19 vaccines among physicians and dentists: a cross-sectional study from India. Journal of Multidisciplinary Healthcare, 16, 161-174.
Mercier, G., Arquizan, C., & Roubille, F. (2020). Understanding the effects of COVID-19 on health care and systems. Lancet Public Health, 5, e524.
Riad, A., Boccuzzi, M., Pold, A., & Krsek, M. (2020). The alarming burden of non-communicable diseases in COVID-19 new normal: Implications on oral health. Oral Dis, 27, 791–792.
Sadoff, J., Gray, G., Vandebosch, A., Cárdenas, V., Shukarev, G., Grinsztejn, B., ... & Douoguih, M. (2022). Final analysis of efficacy and safety of single-dose Ad26. COV2. S. New England Journal of Medicine, 386(9), 847-860.
Strategic Advisory Group of Experts on Immunization (SAGE). Vaccine Hesitancy Survey Questions Related to SAGE Vaccine Hesitancy Matrix. WHO: Geneva, Switzerland.
Troiano, G. & Nardi, A. (2021). Vaccine hesitancy in the era of COVID-19. Public Health, 194, 245–51.
Voysey, M., Clemens, S. A. C., Madhi, S. A., Weckx, L. Y., Folegatti, P. M., Aley, P. K., ... & Bijker, E. (2021). Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK. The Lancet, 397(10269), 99-111.
Wharton, B. R., Doan, K. C., & Wolcott, M. L. (2022). Shoulder injury related to COVID-19 vaccine administration: a case report. JSES Reviews, Reports & Techniques, 2(2), 178-181. https://doi.org/10.1016/j.xrrt.2021.10.005.
Yuen, W.L.P., Loh, S.Y.J., & Wang, D.B. (2022). SIRVA (Shoulder Injury Related to Vaccine Administration) following mRNA COVID-19 Vaccination: case discussion and literature review. Vaccine, 40(18), 2546–2550. https://doi.org/10.1016/j.vaccine.2022.03.037.
Published
2023-12-14
How to Cite
Edunjobi, A. S., Norton, H. E., Aina, B. O., Oluwasanya, A. N., & Babs-Edunjobi, A. M. (2023). A Brief Insight into a Common Short Term Sequel of Covid-19 Vaccination against the SARS-Cov-2 Virus: A Case History and Report of Shoulder Pain Syndrome. European Journal of Science, Innovation and Technology, 3(6), 158-166. Retrieved from https://ejsit-journal.com/index.php/ejsit/article/view/325
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Articles